Urokinase from human urine CAS 9039-53-6

Other names: Yakinase; Urinary active element; U-fibrinogen activator

CAS number: 9039-53-6

Grade: High purity

Specific activity: ≥ 120000IU/mg

Potency: ≥ 75000 IU/mg

Definition of vitality: 37 ℃, pH 8.8, hydrolysis 1 per minute μ The required enzyme quantity for Mole Be Ala Gly Arg-4Na is 1 unit

Solubility: Completely dissolved within 60 seconds (3000IU/ml)

Polymer content: ≥ 85% (M.W.54000)

Pyrogen: in compliance with regulations (20000IU/ml. Kg.)

Endotoxin: ≤ 2 EU/2000IU

Abnormal toxicity: negative (2500IU/0.5 ml/mouse)

HBs Ag: Negative (50000 IU/ml)

Anti HIV I+II: Negative (50000 IU/ml)

Nti-HCV Abs: Negative (50000 IU/ml)

Character: White or almost white freeze-dried powder. Proteinase that hydrolyzes human urine or kidney cells. The natural substrate is fibrinogen. Sensitive to moisture. Soluble in water. Dry powder is relatively stable at 4 ℃, and the stability period of aqueous solution at 4 ℃ is 3 days

Purpose: Biochemical research. It is a protease that cleaves plasminogen to form plasmin. It binds to cell surface receptors (uPARs), regulates cell adhesion, tissue remodeling, and migration, while also activating intracellular signaling pathways. Urokinase is composed of three domains: the amino terminal domain homologous to epidermal growth factor, and the protease domain that binds to the carboxyl terminal through the central kringle domain

Storage: -20 ℃

Company Information

Nanjing Duly Biotech Co.,Ltd 

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