production freeze dryers

　　Principles of clinical and production freeze dryers

　　Freeze drying refers to the process of removing water or other solvents from frozen biological products by sublimation. Sublimation refers to the process of solvents, such as water, like dry ice, which does not pass through a liquid state and changes from a solid to a gaseous state. The product obtained by freeze drying is referred to as a lyophilizer, and the process is referred to as lyophilization.

　　Conventional drying destroys the cells, causing the material to shrink, and the structure of the sample is not destroyed during the freeze-drying process because the solid components are supported by the firm ice on its seat. When the ice sublimates, he leaves the pores in the dry remaining material. This preserves the biological and chemical structure of the product and the integrity of its activity.

　　In the laboratory, lyophilization has many different uses. It is indispensable in many biochemical and pharmaceutical applications. It is used to obtain biological materials that can be preserved for a long period of time, such as microbial culture, blood, enzymes, drugs, In addition to the stability of long-term preservation, its inherent biological activity and structure are retained. To this end, lyophilization is used to prepare tissue samples for structural studies (such as electron microscopy studies), and freeze-drying is also used in chemical analysis to obtain dried samples or to concentrate samples to increase chemical sensitivity. Freeze-drying stabilizes the sample components without changing the chemical composition, making it an ideal analytical aid.

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