Citrus sinensis extract

Specifications

                    Citrus sinensis extract

Name: Hesperidin

Latin Name: Citrus sinensis

Formula: C28H34O15

Testing Method: HPLC

Part of the Plant Used: Peel

Color: Off-white fine powder

In traditional Chinese medicine, the dried peel of the fruit is used, often aged (sometimes until it turns black in color) and sometimes even toasted in a wok. Chen Pimeans aged peel. A decoction is then made from the peel in combination with other herbs. Both the outermost peel (exocarp) and the inner peel (pericarp) are used fordifferent specific medicinal purposes. C. reticulatais also used to make poultices -a paste of finely powdered herbs that is applied externally to help heal internal injuries. Tangerine peel is alsoavailable in pill form.

Quality data

Microbiological data

Addition data

Function

Hesperidin is a flavanone glycoside found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin is believed to play a role in plant defense. It acts as an antioxidant according to in vitro studies. In human nutrition it contributes to the integrity of the blood vessels.

Various preliminary studies reveal novel pharmaceutical properties. Hesperidin reduced cholesterol and blood pressure in rats. In a mouse study large doses of the glucoside hesperidin decreased bone density loss. Another animal study showed protective effects against sepsis. Hesperidin has anti-inflammatory effects. Hesperidin is also a sedative, possibly acting through adenosine receptors.

Some in vitro results applied only to the aglucone form. Hesperidin also showed the ability to penetrate the blood brain barrier in an in vitro model.

Hesperidin, in combination with a flavone glycoside called diosmin, is used in Europe for the treatment of venous insufficiency and hemorrhoids. Hesperidin, rutin and other flavonoids thought to reduce capillary permeability and to have anti-inflammatory action were collectively known as vitamin P.